Major obstacles include the emergence of antimalarial drug resistance, mosquito resistance to insecticides, and inadequate health system performance. 2 Despite such a decline, there remain problems in achieving malaria elimination in Indonesia. 1 The malaria incidence in Indonesia has declined from an annual parasite incidence of 1.8% (422,447 cases) in 2011вЂ“0.8% (218,450 cases) in 2016. The Ministry of Health of the Republic of Indonesia plans to eliminate malaria by 2030. Further molecular analysis of heterozygous females, particularly in malaria-endemic areas, is needed for mapping distribution of G6PD deficiency status in Indonesia. A positive association was shown between G6PD activity and heterozygous females carrying Coimbra genotype, hemizygous males carrying Vanua Lava, Plasmodium falciparum infection in female subjects, and P. A significant association was found between ethnicity and the distribution of G6PD Kaiping in female subjects. No other variants were found in this population.

The prevalence of G6PD deficiency in SCT was 6.3% (24/381 cases), including 4.2% (16/381 cases), 0.5% (2/381 cases), and 1.6% (6/381 cases) for Coimbra, Kaiping, and Vanua Lava variants, respectively. The 381 DNA samples from the previous study during 2013вЂ“2014 were analyzed for G6PD variants by using PCR-restriction fragment length polymorphism (RFLP). For clarity, all of these results are described together. In a previous report from South Central Timor (SCT), Indonesia, we described the prevalence of Vanua Lava, Chatham, and Viangchan variants in this study, other G6PD variants (Kaiping, Coimbra, Gaohe, Canton, and Mahidol) were subsequently analyzed.

However, it can trigger erythrocyte hemolysis in people with glucose 6-phosphate dehydrogenase (G6PD) deficiency. Carolus Hospital, Jakarta, Indonesia, E-mail: Kesara Na-Bangchang and Wanna Chaijaroenkul, Chulabhorn International College of Medicine (CICM), Thammasat University (Rangsit Campus), Patum Thani, Thailand, E-mails: and is an effective anti-hypnozoite drug for Plasmodium vivax and Plasmodium ovale. AuthorsвЂ™ addresses: Novi Sulistyaningrum and Dona Arlinda, Chulabhorn International College of Medicine (CICM), Thammasat University (Rangsit Campus), Patum Thani, Thailand, and National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia, E-mails: and Jontari Hutagalung, Sunarno Sunarno, Intan Sari Oktoberia, Sarwo Handayani, Riyanti Ekowatiningsih, Endah Ariyanti Yusnita, Budi Prasetyorini, and Aulia Rizki, National Institute of Health Research and Development, Ministry of Health, Republic of Indonesia, Jakarta, Indonesia, E-mails: and Emiliana Tjitra, St.

Fokus diagnostic indonesia